PhD positions in visual neuroscience, mood and behavior at the Hebrew University
The laboratory of Dr. Shai Sabbah in the Department of Medical Neurobiology at the Faculty of Medicine, Hebrew University of Jerusalem, is seeking motivated PhD candidates to study retinal and brain circuits that mediate the effect of abnormal lighting on mood.
Light impacts mood in ways we are only beginning to recognize. The short days of winter can trigger seasonal affective disorder (SAD). Whereas, combining light with antidepressant therapy outperforms antidepressant therapy alone, not only in SAD patients, but also in non-seasonal major depressive disorder (MDD). Thus, light affects mood and can augment antidepressant therapy. However, the mechanisms underlying the effect of light on mood have remained unclear. The recent demonstration that a novel retino-thalamo-frontocortical pathway is necessary and sufficient for the induction of depression by abnormal lighting places us in a unique position to resolve this mystery. Our lab studies the synaptic input, functional organization, and broader behavioral significance of this pathway. The mechanistic insights obtained will pave the way for the development of treatments for diverse light-dependent mood disorders.
We use mouse genetic models and combine: (1) in vitro and in vivo functional imaging and electrophysiology, (2) reconstructions of neural circuits using light and electron microscopy, (3)
optogenetic and chemogenetic manipulations of neural activity, and (4) behavioral analysis.
Successful candidates will show solid communication skills in English, ability to work both independently and as part of a research team, strong scientific motivation, and skill in data processing. Experience in one or more of the following would be an advantage: intracranial surgeries, optogenetics, animal behavioral analysis, two-photon imaging, in vivo electrophysiology, and Matlab or python programing.
An application package, including a motivation letter, curriculum vitae, list of publications and names of 2-3 referees, should be sent to Dr. Shai Sabbah.
Department of Medical Neurobiology
Faculty of Medicine
The Hebrew University of Jerusalem, Ein Kerem
P.O. Box 12271, Jerusalem, 9112102 Israel
For a research project in Dr. Inna Gaisler-Salomon’s lab at the University of Haifa, we are looking for a talented, hard-working and fun post-doctoral researcher to study molecular mechanisms of cognitive behavior in a mouse model.
Must have experience working with mice or rats, in vivo, preferably in behavioral models.
Experience with intra-cerebral injections and molecular techniques (PCR, RT-PCR, IHC) – a plus.
Open PhD/Postdoc positions in the Evolutionary Neural Coding Lab at Tel-Aviv University
We are looking for outstanding, highly motivated, and scientifically curious PhD students or postdocs to fill two positions in two ongoing projects in the lab.
In these two projects we investigate different aspect of cortical computation. Our approach is motivated by the notion that to understanding cortical computations we need to study simpler cortical systems. We therefor set to investigate the ancestral cortex of reptiles which is the closest to the first cortex appearing in evolution.
CortiCodes – In this project we set out to study visual processing in turtle cortex. Surprisingly, unlike mammalian primary cortices, the turtle cortex lacks a topographic representation of visual space and exhibits sparse and variable responses to visual stimuli. Consistently, visual stimulation recruits waves and oscillations that span the entire cortex. These characteristics are not in-line with the notion that neurons extract local features of visual space, but rather suggest that global population codes are employed. We will explore these codes by employing a combination of in-vivo and ex-vivo large-scale electrophysiology and behavioral analysis.
Brain state evolution - In this project we set out to investigate the functional role of neuronal organization across different brain states. During such states the neo-cortex and the hippocampus exhibit marked transitions in population patterns, the function of which is still not understood. We will focus on bearded dragons which brain exhibits very organized transitions between states during sleep and wakefulness. We will study the organization and function of these transitions by employing in-vivo electrophysiology, quantitative behavioral analysis and new behavioral paradigms.
Requirements - We encourage candidates with diverse backgrounds to apply. Preference will be given to students with a background in engineering, computer science or physics or students with experience in electrophysiology (extra-cellular or intracellular) or animal behavior.
A project manager for a project in Ethiopia: "project eye opener"
We are looking for a project manager for our project in Ethiopia: "project eye opener". This is a worldwide unique project that combines a humanistic goal and an ambitious scientific agenda. The project, which has been founded 7 years ago, is focused on finding children who have been blind due to congenital cataracts, and due to poor medical resources have not been treated since birth. The cataract-afflicted children typically remain blind due to lack of diagnosis and medical care and all too often die before reaching adulthood. Our project finds these children, makes sure they get surgery, & follows their visual development. This allows studying the bottlenecks for visual functional recovery, and developing a theory of visual development in such circumstances. Eventually, we aim to come up with the best rehabilitation strategies, given our improved understanding of the limitations due to their condition.
If you wish to learn more, please have a look at our website: https://www.project-eyeopener.org/
This is a grand project, which is growing in size.
We are looking for a person that will be able to manage this. The ideal candidate should have the following skills:
1) A PhD in vision science, cognitive psychology, systems neuroscience or related fields (e.g. sensory systems).
2) Basic technical skills (e.g. in visual psychophysics, software writing: matlab or python, and recording techniques: EEG , eye-tracking, etc.).
3) Ability to handle uncertainty and get things done in difficult situations (as is the usual case in Ethiopia: power failure, problems with transportation, etc).
4) High social capabilities, as you need to interact and motivate the local crew and the kids in Ethiopia.
5) Good managing skills, to make sure that the annual trips for data collection, are well planned and meticulously organized.
The person will make 2-3 10-day trips a year for data collection. The rest of the work will be based in the Hebrew University.
The job is based on a soft money position. I currently have secured money for this position for at least 3 years. Securing money for the period after this is probably very likely: We already raised more than 2.5 M euro for this project in the last 7 years.
We are hiring! – Open position for a Senior Scientist.
GliXogen Therapeutics is a new drug discovery company being established in the FutuRx bio-accelerator, located at the Science Park in Ness Ziona. Our company is developing a therapeutic small molecule antagonist of Gli1 transcription factor to enhance remyelination in demyelinating disorders with multiple sclerosis being the primary indication.
We are seeking a highly-motivated individual to join us as a Senior Scientist.
The successful candidate will work as the pivotal scientist during the exciting time of company formation with responsibilities to perform experiments, organize & analyze results, communicate & present findings.
- ·Ph.D. in neuroscience, cell biology or immunology.
- ·Expertise with tissue culture; primary cells and cell lines.
- ·Experience with cell-based assays, qRT-PCR, and IHC/IF using confocal microscopy.
- ·Excellent interpersonal, verbal and written communication skills.
- ·Self-motivated and comfortable in a dynamic company, able to adjust workload based upon changing priorities, with strong organizational skills.
- ·Expertise in the field of remyelination/demyelination and work using iPSC are advantageous.
- ·Estimated starting date is January 2019.
To apply for this job, please send your CV to:
Tenure-Track Position– The Department of Cognitive Sciences The Department of Cognitive Sciences at the University of Haifa
The Department of Cognitive Sciences The Department of Cognitive Sciences at the University of Haifa, Israel, invites applications for an open-rank tenure-track position, beginning in the 2019 academic year. The academic rank will be matched to the candidate’s qualifications.
The deadline for application is November 15 2018. The screening of applications will continue until the position is filled.
The Department of Cognitive Sciences at the University of Haifa, Israel is a new interdisciplinary department, established in 2018 (https://cognition.hevra.haifa.ac.il/).
The department aims to combine different theoretical and methodological points of view to the study of cognitive processes.
We draw on research from Philosophy, Psychology, Linguistics, Computational Sciences and Neuroscience. We are currently in the process of establishing the department, which is starting off as an undergraduate program. This provides a great opportunity for young scientists to influence the development of the curriculum and the department. We are particularly interested in applicants whose research and training is of an interdisciplinary nature within the fields of cognitive sciences such as Linguistics, Psychology, Neuroscience, Philosophy, and Computational Sciences.
The candidate should be able to teach and cooperate scientifically with researchers from varied backgrounds on topics related to cognition. The successful candidate should demonstrate the potential to develop a strong research program, supervise student research, and teach undergraduate and graduate courses.
Final appointment is at the discretion of the Dean and Rector of the University of Haifa
A new postdoc fellowship
A new Weizmann Postdoc program is considering candidates for a Prestigious Postdoctoral Award of the Nella & Leon Benoziyo Center for Neurological Diseases in Molecular and Cellular Neuroscience, or, Brain Sciences (Systems, Computational & Cognitive Neuroscience).
Further information can be found at:
Post-doctoral fellow for an IPS/neuronal project at Teva's R&D site in Natanya
We are offering a three year project focusing on identification of new targets for neurodegenerative diseases. The position will be part of a large scale international consortium bringing together academia and industry, allowing the fellow exposure to diverse cutting edge techniques and science. The major focus would be on assessing neuronal metabolism and bioelectrical activity in human IPSC disease models.
The position will require the deployment of variety of techniques such as: fluorescent high content microscopy, cellular respiration analysis molecular biology electrophysiology and more.
- PhD degree from a leading institution
- Good publication record
- Previous hands on experience with induced pluripotent stem cells, preferably with neuronal cells
- Expertise in mitochondria related assays (including sea horse) is significant advantage
- Background in neurobiology
The work will be done in the pharmacology laboratory (Netanya, Israel). The fellow will have full access and support from a team of preclinical experts including cellular pharmacology, in vivo pharmacology, ADME, toxicology and all other industrial discovery and product development infrastructure and know-how.
Please apply at: https://israel.careers.teva/requisition.html?id=5413